Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Verwandte Produkte (11038)
Verwandte Produkte (11038)
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Paroxetine-d2
0 ImagesArt. -Nr.: HY-111124CAS. Nr.: 923932-43-8Synonyms: BRL29060-d2Paroxetine-d2 (BRL29060-d2) is the deuterated-labeled Paroxetine (HY-122272). Paroxetine (BRL29060) is an orally active and selective serotonin reuptake inhibitor (SSRI) and apoptosis inducer with blood-brain barrier permeability. Paroxetine inhibits nitric oxide synthase and CYP2D6, induces desensitization of 5-HT1A/1B/1D autoreceptors, downregulates 5-HT2 receptors, and promotes the production of inflammatory cytokines. Paroxetine is a weak norepinephrine (NE) uptake inhibitor and possesses antitumor activity. Paroxetine is widely used in research concerning depression, obsessive-compulsive disorder, panic disorder, social phobia, generalized anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, hot flashes, and related conditions.
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Malonyl-L-carnitine-d3 trifluoroacetate
0 ImagesArt. -Nr.: HY-W708734Malonyl-L-carnitine-d3 trifluoroacetate is the deuterium labeled Malonyl-L-carnitine trifluoroacetate.
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1,9-Dibromononane-d18
0 ImagesArt. -Nr.: HY-32874SCAS. Nr.: 150017-89-31,9-Dibromononane-d18 is the deuterium labeled 1,9-Dibromononane.
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Azelastine-d4 hydrochloride
0 ImagesArt. -Nr.: HY-B0462S1CAS. Nr.: 2747915-85-9Azelastine-d4 (hydrochloride) is deuterium-labeled Azelastine (hydrochloride) (HY-B0462).
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Salmeterol-d3 xinafoate
0 ImagesArt. -Nr.: HY-17453SSynonyms: GR 33343X-d3 xinafoateSalmeterol-d3 (xinafoate) is the deuterium labeled Salmeterol xinafoate. Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
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Chloroquine-d5 diphosphate
0 ImagesArt. -Nr.: HY-17589SCAS. Nr.: 1854126-42-3Chloroquine-d5 (diphosphate) is the deuterium labeled Chloroquine (phosphate). Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
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Tri-O-acetyl-D-glucal-13C13C-2
0 ImagesArt. -Nr.: HY-34628S2CAS. Nr.: 478529-37-23,4,6-Tri-O-acetyl-D-glucal-13C-2 is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal.
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D-Threonine-d2
0 ImagesArt. -Nr.: HY-W012874SSynonyms: H-D-Thr-OH-d2D-Threonine-d2 (H-D-Thr-OH-d2) is the deuterium labeled D-Threonine (HY-W012874). D-Threonine (H-D-Thr-OH) is an important non-natural amino acid. D-Threonine serves as a chiral building block for the asymmetric synthesis of compounds. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde under the catalysis of D-threonine aldolase.
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H-Tyr(3-I)-OH-13C6
0 ImagesArt. -Nr.: HY-W008452SCAS. Nr.: 2483735-06-2H-Tyr(3-I)-OH-13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite.
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Vildagliptin-13C5,15N
0 ImagesArt. -Nr.: HY-14291S2CAS. Nr.: 1044741-01-6Synonyms: LAF237-13C5,15N; NVP-LAF 237-13C5,15NVildagliptin-13C5,15N (LAF237-13C5,15N; NVP-LAF 237-13C5,15N) is a 13C- and 15N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.
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Dihydroxy Bendamustine-d8
0 ImagesArt. -Nr.: HY-143930SDihydroxy Bendamustine-d8 is the deuterium labeled Dihydroxy Bendamustine.
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Practolol-d7
0 ImagesArt. -Nr.: HY-119802SCAS. Nr.: 2714414-11-4Practolol-d7 is the deuterium labeled Practolol. Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias.
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Trimethylammonium chloride-13C3,d9
0 ImagesArt. -Nr.: HY-Y0504SCAS. Nr.: 2483824-12-8Trimethylammonium chloride-13C3,d9 is the 13C3,d9-labeled Trimethylammonium chloride (HY-Y0504). Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase.
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DL-Lysine-d9 dihydrochloride
0 ImagesArt. -Nr.: HY-W141978S2DL-Lysine-d9 (dihydrochloride) is the deuterium labeled DL-Lysine.
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Methyl 3-(diethylcarbamoyl)benzoate-d10
0 ImagesArt. -Nr.: HY-W691047SMethyl 3-(diethylcarbamoyl)benzoate-d10 is the deuterium labeled Methyl 3-(diethylcarbamoyl)benzoate (HY-W691047).
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[U-13C,15N]-hTau-441
![[U-13C,15N]-hTau-441](https://file.medchemexpress.com/product_pic/hy-187251s.gif "Click to View [U-13C,15N]-hTau-441 Product Detail")
0 ImagesArt. -Nr.: HY-187251S[U-13C,15N]-hTau-441 is the 13C- and 15N-labeled hTau-441. Abnormal levels and aggregation of hTau-441 in the brain are considered key factors in the pathogenesis of Alzheimer's disease (AD). This isotope can be used in NMR studies of disease mechanisms and in mass spectrometry analysis.
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α-Artemether-d3
0 ImagesArt. -Nr.: HY-W703432CAS. Nr.: 93861-34-8Synonyms: Methoxy-d3α-Artemether-d3 (Methoxy-d3) is the deuterium labeled α-Artemether (HY-137217). α-Artemether is an antimalarial compound.
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19:0 Lyso PE-d5
0 ImagesArt. -Nr.: HY-146844SCAS. Nr.: 2342575-09-919:0 Lyso PE-d5 is deuterium labeled 19:0 Lyso PE.
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DMT-2′O-TBDMS-rA(ac) phosphoramidite-13C
0 ImagesArt. -Nr.: HY-179173SDMT-2′O-TBDMS-rA(ac) phosphoramidite-13C is the 13C-labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite.
